/* hivpave.org — The HIV Vaccine Chronicle
   设计契约 v1.0（竞稿 C 反推）: 档案纸 + 衬线 + 编年时间线 + 结局徽章 */

@font-face{font-family:'Source Serif 4';font-style:normal;font-weight:200 900;font-display:swap;
  src:url(fonts/sourceserif-var-latin.woff2) format('woff2')}
@font-face{font-family:'Source Serif 4';font-style:italic;font-weight:400;font-display:swap;
  src:url(fonts/sourceserif-italic-400-latin.woff2) format('woff2')}
@font-face{font-family:'IBM Plex Mono';font-style:normal;font-weight:400;font-display:swap;
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@font-face{font-family:'IBM Plex Mono';font-style:normal;font-weight:500;font-display:swap;
  src:url(fonts/plexmono-latin-500.woff2) format('woff2')}

:root{
  --paper:#FAF7F2; --card:#FFFFFF;
  --ink:#1F1B16; --body2:#3D372C; --faint:#77705F;
  --red:#B02E2E; --green:#2F6B4F; --amber:#B07A2A;
  --hairline:#E3DCCC; --hairline-2:#C9C0AA;
  --serif:'Source Serif 4','Iowan Old Style',Palatino,Georgia,serif;
  --mono:'IBM Plex Mono','SF Mono',Menlo,monospace;
}
*{margin:0;padding:0;box-sizing:border-box}
html{scroll-behavior:smooth;scroll-padding-top:90px}
body{background:var(--paper);color:var(--ink);font:16.5px/1.7 var(--serif);
  -webkit-font-smoothing:antialiased;text-rendering:optimizeLegibility}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*{animation:none!important;transition:none!important}}
.page{max-width:820px;margin:0 auto;padding:0 30px}
.page-wide{max-width:1060px;margin:0 auto;padding:0 30px}
a{color:var(--red);text-decoration-thickness:1px;text-underline-offset:3px}
a:hover{color:#8C1F1F}
img{max-width:100%;height:auto}
::selection{background:#F3D9C8}

/* ===== masthead ===== */
.masthead{text-align:center;padding:26px 0 18px;border-bottom:2px solid var(--ink)}
.masthead .t{font-size:34px;font-weight:700;letter-spacing:.02em;text-decoration:none;color:var(--ink)}
.masthead .t span{color:var(--red)}
.masthead .t:hover{color:var(--ink)}
.masthead .d{margin-top:6px;font-size:12px;letter-spacing:.3em;color:var(--faint);text-transform:uppercase}
.nav{display:flex;flex-wrap:wrap;justify-content:center;gap:4px 26px;padding:13px 0;
  border-bottom:1px solid var(--hairline-2);font-family:var(--mono);font-size:12.5px;letter-spacing:.08em}
.nav a{color:var(--body2);text-decoration:none}
.nav a:hover{color:var(--red)}
.nav a[aria-current]{color:var(--red);text-decoration:underline;text-underline-offset:5px}

.langbar{display:flex;justify-content:center;gap:2px 18px;padding:10px 0;
  border-bottom:1px solid var(--hairline-2);font-family:var(--mono);font-size:11.5px;letter-spacing:.1em}
.langbar a{color:var(--faint);text-decoration:none}
.langbar a:hover{color:var(--red)}
.langbar a.on{color:var(--ink);text-decoration:underline;text-underline-offset:4px}

/* ===== hero ===== */
.hero{padding:60px 0 30px;text-align:center}
.hero .year{font-size:clamp(72px,14vw,120px);line-height:1;font-weight:700;letter-spacing:-.03em;
  color:var(--red);font-variant-numeric:tabular-nums}
.hero h1{font-size:clamp(24px,4vw,34px);font-weight:400;font-style:italic;margin-top:10px}
.hero .byline{margin-top:18px;font-size:14px;color:var(--faint)}
.hero .lede{max-width:620px;margin:26px auto 0;font-size:17.5px;color:var(--body2)}
.rule{height:1px;background:var(--hairline-2);margin:34px 0}

/* ===== chronicle timeline ===== */
.timeline{padding:20px 0 50px}
.entry{display:grid;grid-template-columns:96px 26px 1fr;gap:0 18px;position:relative;padding-bottom:44px}
.entry .yr{font-size:26px;font-weight:700;text-align:right;line-height:1.1;font-variant-numeric:tabular-nums}
.entry .yr small{display:block;font-size:11px;font-weight:400;letter-spacing:.14em;color:var(--faint);margin-top:5px}
.entry .spine{position:relative}
.entry .spine::before{content:"";position:absolute;left:12px;top:6px;bottom:-6px;width:1px;background:var(--hairline-2)}
.entry:last-child .spine::before{bottom:auto;height:20px}
.entry .dot{position:absolute;left:6px;top:8px;width:13px;height:13px;border-radius:50%;
  background:var(--paper);border:2.5px solid var(--red)}
.entry.open .dot{border-color:var(--green);background:var(--green)}
.entry.mixed .dot{border-color:var(--amber)}
.entry.prep .dot{border-color:var(--green);background:transparent}
.entry .body h2{font-size:21px;font-weight:700;letter-spacing:-.005em;margin:2px 0 6px}
.entry .body h2 .tid{font-family:var(--mono);font-size:14px;font-weight:500;color:var(--red);letter-spacing:.02em;white-space:nowrap}
.entry.open .tid{color:var(--green)}
.entry.prep .tid{color:var(--green)}
.entry .body p{font-size:16.5px;color:var(--body2);max-width:580px}
.entry .body .quote{margin-top:12px;padding-left:16px;border-left:3px solid var(--red);
  font-style:italic;color:var(--faint);font-size:15.5px;max-width:520px}
.badge{display:inline-block;font-family:var(--mono);font-size:10.5px;letter-spacing:.16em;
  padding:3px 9px;margin-top:12px;border:1px solid var(--ink);text-decoration:none}
.badge.stop,.badge:link.stop{border-color:var(--red);color:var(--red)}
.badge.go{border-color:var(--green);color:var(--green)}
.badge.mixed{border-color:var(--amber);color:var(--amber)}
.badge:hover{background:transparent;opacity:.75}

/* ===== section headers ===== */
.sec-head{margin:56px 0 26px;display:flex;align-items:baseline;justify-content:space-between;gap:18px;flex-wrap:wrap}
.sec-head h2{font-size:27px;font-weight:700;letter-spacing:-.01em}
.sec-head .count{font-family:var(--mono);font-size:12px;color:var(--faint);letter-spacing:.1em}
.lede-block{font-size:17.5px;color:var(--body2);max-width:680px;margin-bottom:28px}
.lede-block strong{color:var(--ink)}

/* ===== archive cards (trials page) ===== */
.arc{display:grid;grid-template-columns:150px 1fr 140px;background:var(--card);
  border:1px solid var(--hairline);border-left:5px solid var(--faint);margin-bottom:16px}
.arc.stopped{border-left-color:var(--red)}
.arc.partial{border-left-color:var(--amber)}
.arc.continued,.arc.open{border-left-color:var(--green)}
.arc .no{font-family:var(--mono);padding:20px 16px;border-right:1px dashed var(--hairline);font-size:14px}
.arc .no b{display:block;font-size:15px;letter-spacing:.02em}
.arc .no small{display:block;font-size:10px;color:var(--faint);letter-spacing:.14em;margin:4px 0 6px}
.arc .bd{padding:20px 24px}
.arc h3{font-size:19px;font-weight:700;margin-bottom:4px}
.arc .meta{font-family:var(--mono);font-size:12.5px;color:var(--faint);margin-bottom:10px}
.arc .finding{font-size:15.5px;color:var(--body2)}
.arc .finding em{font-style:italic}
.arc .outcome{display:flex;flex-direction:column;justify-content:center;align-items:center;gap:6px;
  font-family:var(--mono);font-size:11px;letter-spacing:.12em;border-left:1px dashed var(--hairline);padding:12px;text-align:center}
.outcome .word{font-size:13.5px;font-weight:500}
.stopped .outcome .word{color:var(--red)}
.partial .outcome .word{color:var(--amber)}
.continued .outcome .word,.open .outcome .word{color:var(--green)}

/* ===== generic content blocks ===== */
.cols-2{display:grid;grid-template-columns:1fr 1fr;gap:28px}
@media(max-width:720px){.cols-2{grid-template-columns:1fr}}
.pillar{background:var(--card);border:1px solid var(--hairline);padding:26px 28px;margin-bottom:18px}
.pillar h3{font-size:19px;font-weight:700;margin-bottom:8px}
.pillar h3 .n{font-family:var(--mono);font-size:13px;color:var(--red);margin-right:10px}
.pillar p{font-size:15.5px;color:var(--body2)}
.pillar .src{margin-top:10px;font-family:var(--mono);font-size:11.5px;color:var(--faint)}
.stat-strip{display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));gap:1px;
  background:var(--hairline-2);border:1px solid var(--hairline-2);margin:28px 0}
.stat-strip .cell{background:var(--card);padding:20px;text-align:center}
.stat-strip .v{font-size:30px;font-weight:700;font-variant-numeric:tabular-nums;color:var(--red)}
.stat-strip .v.gr{color:var(--green)}
.stat-strip .k{font-family:var(--mono);font-size:11px;letter-spacing:.12em;color:var(--faint);margin-top:6px}
table.cmp{width:100%;border-collapse:collapse;background:var(--card);font-size:15px;margin:20px 0}
table.cmp th{font-family:var(--mono);font-size:11.5px;letter-spacing:.1em;text-align:left;
  color:var(--faint);border-bottom:2px solid var(--ink);padding:10px 12px;font-weight:500}
table.cmp td{border-bottom:1px solid var(--hairline);padding:12px;color:var(--body2);vertical-align:top}
table.cmp td.y{font-family:var(--mono);font-weight:500;color:var(--ink);white-space:nowrap}
table.cmp tr:last-child td{border-bottom:none}

/* ===== glossary ===== */
dl.gloss{margin:24px 0}
dl.gloss dt{font-weight:700;font-size:18px;margin-top:22px}
dl.gloss dt .mono-tag{font-family:var(--mono);font-size:12px;color:var(--red);margin-left:8px;letter-spacing:.06em}
dl.gloss dd{margin-top:4px;color:var(--body2);max-width:640px}
dl.gloss dd .plain{display:block;margin-top:2px;font-style:italic;color:var(--faint);font-size:15px}

/* ===== article/updates ===== */
.post-meta{font-family:var(--mono);font-size:12px;color:var(--faint);letter-spacing:.1em;margin:14px 0 30px}
.post-body p{margin:0 0 20px;max-width:680px;color:var(--body2);font-size:17px}
.post-body h2{font-size:24px;font-weight:700;margin:38px 0 14px}
.post-body blockquote{border-left:3px solid var(--red);padding-left:18px;margin:26px 0;
  font-style:italic;font-size:18px;color:var(--body2);max-width:600px}
.post-body blockquote cite{display:block;font-style:normal;font-family:var(--mono);font-size:12px;color:var(--faint);margin-top:8px}
.figure{margin:30px 0}
.figure img{display:block;width:100%;border:1px solid var(--hairline)}
.figure figcaption{font-family:var(--mono);font-size:11.5px;color:var(--faint);margin-top:8px;letter-spacing:.06em}
.post-list{margin:26px 0}
.post-list a{display:block;padding:22px 4px;border-bottom:1px solid var(--hairline);text-decoration:none}
.post-list a:hover h3{color:var(--red)}
.post-list .pm{font-family:var(--mono);font-size:11.5px;color:var(--faint);letter-spacing:.1em}
.post-list h3{font-size:20px;font-weight:700;margin:6px 0 4px;color:var(--ink)}
.post-list .dek{font-size:15.5px;color:var(--body2)}

/* ===== footer ===== */
footer{border-top:2px solid var(--ink);margin-top:60px;padding:22px 0 44px}
.foot-grid{display:flex;justify-content:space-between;gap:24px;flex-wrap:wrap;
  font-family:var(--mono);font-size:11.5px;color:var(--faint);letter-spacing:.08em}
.foot-grid a{color:var(--faint)}
.foot-grid a:hover{color:var(--red)}

/* ===== utilities ===== */
.mono{font-family:var(--mono)}
.faint{color:var(--faint)}
.small{font-size:13.5px}
.center{text-align:center}
.mt0{margin-top:0}
.notice{background:var(--card);border:1px solid var(--hairline-2);padding:18px 22px;
  font-size:14.5px;color:var(--body2);margin:26px 0}
.notice b{color:var(--ink)}
@media print{.nav,footer,.badge{display:none}body{font-size:12pt}.arc{break-inside:avoid}}
@media(max-width:640px){
  .page,.page-wide{padding:0 18px}
  .entry{grid-template-columns:64px 20px 1fr;gap:0 12px;padding-bottom:34px}
  .entry .yr{font-size:20px}
  .arc{grid-template-columns:1fr}
  .arc .no{border-right:none;border-bottom:1px dashed var(--hairline);display:flex;gap:8px;align-items:baseline;padding:12px 16px}
  .arc .outcome{border-left:none;border-top:1px dashed var(--hairline);flex-direction:row;justify-content:flex-start}
}